ACE2

Product Description

ACE2 is available at Gentaur for nextb week delivery

Background:  Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis. Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, a vasodilator. Also removes the C-terminal residue from three other vasoactive peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin. Also cleaves other biological peptides, such as apelins, casomorphins and dynorphin A with high efficiency. In addition, ACE2 C-terminus is homologous to collectrin and is responsible for the trafficking of the neutral amino acid transporter SL6A19 to the plasma membrane of gut epithelial cells via direct interaction, regulating its expression on the cell surface and its catalytic activity.

Reactivity:  COVID-19

Applications:  ELISA WB

Concentration:  PBS,pH7.2

Purification&Purity:  The protein was purified from HEK293 and the purity is > 95% (by SDS-PAGE)..

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  Full length protein

Alternative Name:  ORF3a protein; Severe acute respiratory syndrome coronavirus 2; SARS-CoV-2; HCoV-19; SARS2; 2019-nCoV; COVID-19; COVID-19 virus; Human coronavirus 2019

Immunogen:  .

Host:  HEK293

Swiss-Prot: Q9BYF1