Immunoglobulins or antibodies are heavy plasma’s proteins, carrying sugar chains on their amino acids residues (N-link glycosylation or O-linked glycosylation). Antibodies protect the body from harmful pathogens. After the recognition of the antigen by the immune system, B cells differentiate into memory B cells and plasma cells. The plasma cells then produce the specific antibodies of antigen. Several B cells produce a heterogeneous mixture of antibodies, each one targeting a different epitope on the same antigen.
The production of polyclonal antibodies through rabbit immunization is a time- and cost-effective approach, which produces large quantities of high specific antibodies with a high affinity.