anti- ACHE antibody

Product Description

anti- ACHE antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally..

Immunogen: acetylcholinesterase (Yt blood group)

Synonyms: Acetylcholinesterase, ACHE, ARACHE, N ACHE, YT

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab00083( ACHE Antibody) at dilution of 1:100

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Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab00083(ACHE antibody) at dilution of 1:1000

Gene ID: 43

Research Area: Metabolism

Uniprot ID: P22303