anti- Aconitase 2 antibody

Product Description

anti- Aconitase 2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: ACO2(aconitate hydratase, mitochondrial) is also named as citrate hydro-lyase and belongs to the aconitase/IPM isomerase family. It plays a key function in cellular energy production, and loss of its activity has a major impact on cellular and organismal survival. Western blot shows two bands of 83 kDa and 40 kDa. The 40 kDa fragment decreases with age and oxidative stress, whereas other fragmentation products with molecular weights between 40 and 83 kDa increased with age and MnSOD(mitochondrial manganese superoxide dismutase) deficiency(PMID:12459471). Defects in ACO2 are the cause of infantile cerebellar-retinal degeneration(ICRD)..

Immunogen: aconitase 2, mitochondrial

Synonyms: Gene symbol ACO2 Synonyms ACO2, Aconitase, aconitase 2, aconitase 2, mitochondrial, ACONM, Citrate hydro lyase

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:200

Image 1: Immunohistochemistry of paraffin-embedded human lung cancer using FNab00088(ACO2 antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of ( 4% PFA ) fixed HeLa cells using FNab00088(ACO2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab00088(ACO2 antibody) at dilution of 1:400

Gene ID: 50

Research Area: Metabolism

Uniprot ID: Q99798