anti- ACTN4 antibody

Product Description

anti- ACTN4 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein(Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation(PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions(By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA(PubMed:22351778)..

Immunogen: actinin, alpha 4

Synonyms: ACTININ 4, actinin, alpha 4, ACTN4, Alpha actinin 4, DKFZp686K23158, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF, IP, FC

Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:500-1:5000; IF: 1:10-1:100

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab00123(ACTN4 antibody) at dilution of 1:100

Image 2: .

Image 3:

Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00123(ACTN4 antibody) at dilution of 1:500

Gene ID: 81

Research Area: Metabolism

Uniprot ID: O43707