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Product Description
anti- ACVRL1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well..
Immunogen: activin A receptor type II-like 1
Synonyms: Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I
Reactivity: Human
Tested Application: ELISA, WB, IHC, FC, IP
Recommended dilution: WB: 1:200-1:1000; IHC: 1:100-1:400; IP: 1:200-1:1000
Image 1: Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab00131(ACVRL1 Antibody) at dilution of 1:200
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab00131(ACVRL1 antibody) at dilution of 1:400
Gene ID: 94
Research Area: Metabolism
Uniprot ID: P37023
