anti- ADAR1 antibody

Product Description

anti- ADAR1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon(IFN) inducible ?150 kDa protein and a constitutively expressed N-terminally truncated ?110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria(DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802)..

Immunogen: adenosine deaminase, RNA-specific

Synonyms: ADAR, ADAR1, adenosine deaminase, RNA, DRADA, DSH, DSRAD, G1P1, IFI 4, IFI4, Interferon inducible protein 4, K88dsRBP, p136

Reactivity: Human, Mouse, Rat, Pig

Tested Application: ELISA, IHC, IF, WB, IP

Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:2000; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human gliomas using FNab00150(ADAR1 antibody) at dilution of 1:50

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab00150(ADAR1 Antibody) at dilution of 1:1000

Gene ID: 103

Research Area: Metabolism

Uniprot ID: P55265