anti- AEG-1/MTDH-Specific antibody

Product Description

anti- AEG-1/MTDH-Specific antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22, the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH..

Immunogen: metadherin

Synonyms: 3D3, 3D3/LYRIC, AEG 1, AEG1, LYRIC, LYRIC/3D3, metadherin, Metastasis adhesion protein, MTDH, Protein LYRIC

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded mouse brain using FNab00189(AEG-1 antibody) at dilution of 1:200

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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab00189(AEG-1 antibody) at dilution of 1:1000

Gene ID: 92140

Research Area: Metabolism

Uniprot ID: Q86UE4