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Product Description
anti- AFF4 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Key component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins(ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression..
Immunogen: AF4/FMR2 family, member 4
Synonyms: AF4/FMR2 family member 4, AF4/FMR2 family, member 4, AF5Q31, AFF4, MCEF, Protein AF 5q31
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IP
Recommended dilution: WB: 1:200-1:2000; IP: 1:200-1:1000
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Image 4: L02 cells were subjected to SDS PAGE followed by western blot with FNab00197(AFF4 antibody) at dilution of 1:500
Gene ID: 27125
Research Area: Metabolism
Uniprot ID: Q9UHB7
