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Product Description
anti- Aggrecan antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Aggrecan(ACAN), also named as CSPCP, AGC1 and MSK16, belongs to the aggrecan/versican proteoglycan family(also including versican, brevican and neurocan). It is a major component of extracellular matrix of cartilagenous tissues. A major function of aggrecan is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. This polyclonal antibody raised against 1-298aa of human aggrecan reveals a band of 70 kDa, which is consistent with the molecular weight of degradation product generated by proteolysis at the aggrecanase site(PMID: 7852317; 9337874)..
Immunogen: aggrecan
Synonyms: ACAN, AGC1, AGCAN, aggrecan, CSPG1, CSPGCP, MSK16, SEDK
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500-1:1000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human cartilage tissue slide using FNab00213(ACAN Antibody) at dilution of 1:100
Image 2: .
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Image 4: ROS1728 cells were subjected to SDS PAGE followed by western blot with FNab00213(ACAN Antibody) at dilution of 1:600
Research Area: Metabolism
Uniprot ID: P16112
