anti- AKAP10 antibody

Product Description

anti- AKAP10 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase(By similarity)..

Immunogen: A kinase(PRKA) anchor protein 10

Synonyms: AKAP10, D AKAP2, AKAP 10, PRKA10, D AKAP 2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-200

Image 1: Immunohistochemistry of paraffin-embedded human cervical cancer using FNab00250(AKAP10 antibody) at dilution of 1:100

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00250(AKAP10 antibody) at dilution of 1:500

Gene ID: 11216

Research Area: Metabolism

Uniprot ID: O43572