anti- AKTIP antibody

Product Description

anti- AKTIP antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein..

Immunogen: AKT interacting protein

Synonyms: AKT interacting protein, AKTIP, FT1, FTS, Fused toes protein homolog

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat brain using FNab00274(AKTIP antibody) at dilution of 1:100

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Image 4: mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with FNab00274( AKTIP Antibody) at dilution of 1:1000

Gene ID: 64400

Research Area: Metabolism

Uniprot ID: Q9H8T0