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Product Description
anti- Alpha-2-macroglobulin antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: Alpha-2-macroglobulin, also known as ?2-macroglobulin(?2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimers disease..
Immunogen: alpha-2-macroglobulin
Synonyms: A2M, Alpha 2 M, alpha 2 macroglobulin, CPAMD5, DKFZp779B086, FWP007, S863 7, ?-2M
Reactivity: Human
Tested Application: ELISA, IHC, WB
Recommended dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:50-1:500; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human liver slide using FNab00341(A2M Antibody) at dilution of 1:50
Image 2: .
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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00341(A2M antibody) at dilution of 1:1000
Gene ID: 2
Research Area: Metabolism
Uniprot ID: P01023
