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Product Description
anti- Alpha B Crystallin antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Alpha B-crystallin, encoded by CRYAB gene, is multifunctional, serving as both a major structural protein in the lens and a small heat-shock protein in other tissues in mammals. Alpha B-crystallin may contribute to the transparency and refractive index of the lens. Single nucleotide polymorphisms(SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. Mutations in the CRYAB gene cause distinct clinical phenotypes including isolated posterior polar cataract, myofibrillar myopathy, cardiomyopathy, or a multisystemic disorder combining all these features. Impairment of alpha-B crystallin dimerization may be relevant to the pathogenesis of these disorders..
Immunogen: crystallin, alpha B
Synonyms: Alpha B Crystallin, Alpha crystallin B chain, Alpha(B) crystallin, CRYA2, CRYAB, crystallin, alpha B, CTPP2, Heat shock protein beta 5, HSPB5, Rosenthal fiber component
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:2000
Image 1: Immunohistochemistry of paraffin-embedded mouse heart tissue using FNab00325(CRYAB antibody) at dilution of 1:100
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Image 4: human heart tissue were subjected to SDS PAGE followed by western blot with FNab00325(CRYAB antibody) at dilution of 1:500
Research Area: Metabolism
Uniprot ID: P02511
