anti- alpha-synuclein antibody

Product Description

anti- alpha-synuclein antibody is available at Gentaur for Next week Delivery.

Purification: protein A+G purified

Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene..

Immunogen: synuclein, alpha (non A4 component of amyloid precursor)

Synonyms: Alpha synuclein, NACP, PARK1, PARK4, SNCA

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000

Image 1: Immunohistochemistry of paraffin-embedded mouse brain using FNab09891(SNCA antibody) at dilution of 1:1000

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09891(SNCA antibody) at dilution of 1:1000

Gene ID: 6622

Research Area: Metabolism

Uniprot ID: P37840