anti- ALPL antibody

Product Description

anti- ALPL antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney(tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. ALPL(Alkaline phosphatase, tissue-nonspecific isozyme) is also named as AP-TNAP, TNSALP and belongs to the alkaline phosphatase family. It can exsit as a homodimer with the molecular weight of 140 kDa(PMID:18724009). ALPL was synthesized as a 66-kDa endo-b-N-acetylglucos-aminidase H(Endo H)-sensitive form, and processed to an 80-kDa mature form, which is anchored to the plasma membrane via glycosylphosphatidylinositol(GPI)(PMID:10839996).This antibody can bind the four mentioned alkaline phosphatases..

Immunogen: alkaline phosphatase, liver/bone/kidney

Synonyms: Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, Alkaline phosphatase tissue nonspecific isozyme, ALPL, BLAP, Bone Alkaline Phosphatase, NBAP

Reactivity: Human

Tested Application: ELISA, WB, IHC, FC

Recommended dilution: WB: 1:500-1:3000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab00347(ALPL antibody) at dilution of 1:50

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00347(ALPL antibody) at dilution of 1:800

Gene ID: 249

Research Area: Metabolism

Uniprot ID: P05186