anti- AMBRA1 antibody

Product Description

anti- AMBRA1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. AMBRA1 (Activating molecule in BECN1-regulated autophagy protein 1), also known as WDR94 or KIAA1736, is a 1, 298 amino acid protein that contains three WD repeats. Localized to cytoplasmic vesicles, AMBRA1 functions to control protein turnover, cell proliferation and cell survival during neuronal development, thereby playing an important role in autophagy and the development of the nervous system. Multiple isoforms of AMBRA1 exist due to alternative spicing events..

Immunogen: autophagy/beclin-1 regulator 1

Synonyms: AMBRA1, autophagy/beclin 1 regulator 1, FLJ20294, KIAA1736, WDR94

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat kidney using FNab00356(AMBRA1 antibody) at dilution of 1:50

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00356(AMBRA1 antibody) at dilution of 1:1000

Gene ID: 55626

Research Area: Metabolism

Uniprot ID: Q9C0C7