anti- AMPK beta 2 antibody

Product Description

anti- AMPK beta 2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene..

Immunogen: protein kinase, AMP-activated, beta 2 non-catalytic subunit

Synonyms: AMPK beta 2, AMPK subunit beta 2, PRKAB2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat kidney using FNab00378(PRKAB2 antibody) at dilution of 1:100

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Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab00378(PRKAB2 antibody) at dilution of 1:1000

Gene ID: 5565

Research Area: Metabolism

Uniprot ID: O43741