anti- ANGPTL4 antibody

Product Description

anti- ANGPTL4 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix(ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation(By similarity)..

Immunogen: angiopoietin-like 4

Synonyms: Angiopoietin like 4, Angiopoietin like protein 4, Angiopoietin related protein 4, ANGPTL2, ANGPTL4, ARP4, FIAF, HFARP, NL2, PGAR, pp1158, PSEC0166, UNQ171/PRO197

Reactivity: Human, Mouse

Tested Application: ELISA, IHC, IF, IP, WB

Recommended dilution: WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200; IP: 1:200-1:2000

Image 1: Immunohistochemistry of paraffin-embedded human kidney slide using FNab00399(ANGPTL4 Antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of ( -20°C Ethanol) fixed HEK-293 cells using FNab00399 (ANGPTL4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00399(ANGPTL4 Antibody) at dilution of 1:1000

Gene ID: 51129

Research Area: Metabolism

Uniprot ID: Q9BY76