anti- ARF1 antibody

Product Description

anti- ARF1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor(AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression(LTD)..

Immunogen: ADP-ribosylation factor 1

Synonyms:

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IF, IHC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab00529(ARF1 Antibody) at dilution of 1:50

Image 2: .

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab00529(ARF1 antibody) at dilution of 1:500

Gene ID: 375

Research Area: Metabolism

Uniprot ID: P84077