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Product Description
anti- ARHGEF1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation..
Immunogen: Rho guanine nucleotide exchange factor(GEF) 1
Synonyms: ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5, ARHG1
Reactivity: Human, Rat
Tested Application: ELISA, IHC
Recommended dilution: IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded rat lung using FNab10091(PER2 antibody) at dilution of 1:50
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Gene ID: 9138
Research Area: Metabolism
Uniprot ID: Q92888
