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Product Description
anti- ARHGEF4 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression..
Immunogen: Rho guanine nucleotide exchange factor(GEF) 4
Synonyms: KIAA1112
Reactivity: Human, Mouse
Tested Application: ELISA, IHC, WB
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab00562(ARHGEF4 Antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00562(ARHGEF4 Antibody) at dilution of 1:1000
Gene ID: 50649
Research Area: Metabolism
Uniprot ID: Q9NR80
