anti- ARL2 antibody

Product Description

anti- ARL2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle..

Immunogen: ADP-ribosylation factor-like 2

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human ovary tumor using FNab00574(ARL2 antibody) at dilution of 1:100

Image 2: .

Image 3:

Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab00574(ARL2 antibody) at dilution of 1:500

Gene ID: 402

Research Area: Metabolism

Uniprot ID: P36404