anti- ATF2 antibody

Product Description

anti- ATF2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene.

Immunogen: activating transcription factor 2

Synonyms: CREB2, CREBP1

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human gastric cancer using FNab00660(ATF2 antibody) at dilution of 1:100

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Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab00660(ATF2 antibody) at dilution of 1:1000

Gene ID: 1386

Research Area: Metabolism

Uniprot ID: P15336