Euro
British Pound
US Dollar
Product Description
anti- ATF6B antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resulting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody could recognize ATF6 beta (110kd) and its cleaved forms(60,80kd )(PMID: 11256944).
Immunogen: activating transcription factor 6 beta
Synonyms: CREBL1, G13
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF, IP
Recommended dilution: WB: 1:1000-1:4000; IP:1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Image 1: Immunohistochemistry of paraffin-embedded human brain using FNab00665(ATF6B antibody) at dilution of 1:100
Image 2: .
Image 3:
Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab00665(ATF6B antibody) at dilution of 1:1000
Gene ID: 1388
Research Area: Metabolism
Uniprot ID: Q99941
