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Product Description
anti- ATG4B antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms..
Immunogen: ATG4 autophagy related 4 homolog B(S. cerevisiae)
Synonyms: APG4B, AUTL1, KIAA0943
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab00674(ATG4B antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab00674(ATG4B antibody) at dilution of 1:800
Gene ID: 23192
Research Area: Metabolism
Uniprot ID: Q9Y4P1
