Product Description
anti- ATP7B antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD)..
Immunogen: ATP7B
Synonyms: PWD, WC1, WD, WND
Reactivity: Human
Tested Application: IHC
Recommended dilution: IHC: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab09904( ATP7B antibody) at dilution of 1:100
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Gene ID: 540
Research Area: Metabolism
Uniprot ID: P35670