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Product Description
anti- ATP8A1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine(PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine(PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells..
Immunogen: ATPase, aminophospholipid transporter(APLT), class I, type 8A, member 1
Synonyms: ATP8A1, ATPase II, ATPASEII, ATPIA, ATPP2, Chromaffin granule ATPase II
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:2000
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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00728(ATP8A1 antibody) at dilution of 1:1000
Gene ID: 10396
Research Area: Metabolism
Uniprot ID: Q9Y2Q0
