Euro
British Pound
US Dollar
Product Description
anti- ATX3,ATXN3 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: ATXN3, which has deubiquitinase activity and act as a component of the ubiquitin proteasome system, plays a role in transcriptional regulation and neuroprotection. ATXN3 interacts with RAD23, HHR23A and HHR23B, involves in the pathology of MJD. ATXN3 is a mixed-linkage, chain-editing enzyme and that the UIM region of ATXN3 regulates its substrate specificity. Contains an N-terminal deubiquitinating domain, called the Josephin domain, followed by 2 ubiquitin-interacting motifs (UIMs) and a polyQ tract near the C terminus. ATXN3 can be phosphorylated in a protein casein kinase-2-dependent manner, thus the MW would be larger than the predicted one..
Immunogen: ataxin 3
Synonyms: AT3, ataxin 3, ATX3, ATXN3, JOS, MJD, MJD1, SCA3
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500-1:1000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab00739(ATX3,ATXN3 antibody) at dilution of 1:100
Image 2: .
Image 3:
Image 4: mouse pancreas tissue were subjected to SDS PAGE followed by western blot with FNab00739(ATX3,ATXN3 antibody) at dilution of 1:500
Research Area: Metabolism
Uniprot ID: P54252
