anti- Autotaxin antibody

Product Description

anti- Autotaxin antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Hydrolyzes lysophospholipids to produce lysophosphatidic acid(LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor..

Immunogen: ectonucleotide pyrophosphatase/phosphodiesterase 2

Synonyms: ATX, ATX X, Autotaxin, E NPP 2, ENPP2, FLJ26803, LysoPLD, PD IALPHA, PDNP2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recommended dilution: WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab00749(ENPP2 Antibody) at dilution of 1:50

Image 2: .

Image 3:

Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00749(ENPP2 antibody) at dilution of 1:500

Gene ID:

Research Area: Metabolism

Uniprot ID: Q13822