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Product Description
anti- BARD1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage..
Immunogen: BRCA1 associated RING domain 1
Synonyms: BARD 1, BARD1, BRCA1 associated RING domain 1
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:1000
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Image 4: SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab00803( BARD1 Antibody) at dilution of 1:300
Gene ID: 580
Research Area: Metabolism
Uniprot ID: Q99728
