anti- BCL2 antibody

Product Description

anti- BCL2 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785)..

Immunogen: B-cell CLL/lymphoma 2

Synonyms: Apoptosis regulator Bcl 2, B cell CLL/lymphoma 2, BCL2, Oncogene B cell leukemia 2

Reactivity: Human

Tested Application: ELISA, WB, IP, IHC

Recommended dilution: WB: 1:1000-1:10000; IP: 1:500-1:5000; IHC: 1:100-1:2000

Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab00840(BCL2 Antibody) at dilution of 1:100

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Image 4: U-937 cells were subjected to SDS PAGE followed by western blot with FNab00840(BCL2 Antibody) at dilution of 1:6000

Gene ID: 596

Research Area: Metabolism

Uniprot ID: P10415