anti- Beclin 1 antibody

Product Description

anti- Beclin 1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Beclin-1(BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy..

Immunogen: beclin 1, autophagy related

Synonyms: ATG6, Beclin 1, beclin 1, autophagy related, beclin1, BECN1, GT197, Protein GT197, VPS30

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB,IF

Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab00860(Beclin 1 antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of NIH/3T3 cells using Beclin 1 Antibody at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with FNab00860(Beclin 1 Antibody) at dilution of 1:1000

Gene ID: 8678

Research Area: Metabolism

Uniprot ID: Q14457