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Product Description
anti- BIN1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described..
Immunogen: bridging integrator 1
Synonyms: AMPHL
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50
Image 1: Immunohistochemistry of paraffin-embedded human kidney using FNab00897(BIN1 antibody) at dilution of 1:100
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab00897(BIN1 antibody) at dilution of 1:1000
Gene ID: 274
Research Area: Metabolism
Uniprot ID: O00499
