Euro
British Pound
US Dollar
Product Description
anti- BORIS antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: CTCFL, also named BORIS(for brother of the regulator of imprinted sites) is a paralogue of the 11 zinc-finger transcription factor, CTCF. It is predominantly expressed in spermatocytes in the testis, also can be found in tumors and cancer cell lines. It mainly participates in insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. It has a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region(ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2..
Immunogen: CCCTC-binding factor(zinc finger protein)-like
Synonyms: BORIS, Cancer/testis antigen 27, CCCTC binding factor, CT27, CTCF like protein, CTCF paralog, CTCF T, CTCFL, dJ579F20.2, Zinc finger protein CTCF T
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IF
Recommended dilution: WB: 1:500-1:2000; IF: 1:10-1:100
Image 1:
Image 2: Immunofluorescent analysis of MCF-7 cells, using FNab00932(BORIS antibody) at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red)..
Image 3:
Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab00932(BORIS antibody) at dilution of 1:1000
Research Area: Metabolism
Uniprot ID: Q8NI51
