anti- BRAF antibody

Product Description

anti- BRAF antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene..

Immunogen: v-raf murine sarcoma viral oncogene homolog B1

Synonyms: BRAF1, RAFB1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human malignant melanoma tissue slide using FNab00941( BRAF Antibody) at dilution of 1:100

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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00941(BRAF antibody) at dilution of 1:1000

Gene ID: 673

Research Area: Metabolism

Uniprot ID: P15056