anti- c-MYC antibody

Product Description

anti- c-MYC antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: MYC contains one basic helix-loop-helix(bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC [PMID: 12189186].

Immunogen: v-myc myelocytomatosis viral oncogene homolog(avian)

Synonyms: BHLHe39, c Myc, c-Myc, MRTL, MYC, Myc proto oncogene protein, Proto oncogene c Myc, Transcription factor p64

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IP, IHC

Recommended dilution: WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:200

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab01791(MYC antibody) at dilution of 1:50

Image 2: .

Image 3: IP Result of anti-MYC (IP: FNab01791, 3ug; Detection: FNab01791 1:500) with HL-60 cells lysate 1200ug.

Image 4: Raji cells were subjected to SDS PAGE followed by western blot with FNab01791(MYC antibody) at dilution of 1:1000

Gene ID:

Research Area: Metabolism

Uniprot ID: P01106