anti- CACNA1B antibody

Product Description

anti- CACNA1B antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated'(HVA) group and are blocked by omega-conotoxin-GVIA(omega-CTx-GVIA) and by omega-agatoxin-IIIA(omega-Aga-IIIA). They are however insensitive to dihydropyridines(DHP), and omega-agatoxin-IVA(omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons..

Immunogen: calcium channel, voltage-dependent, N type, alpha 1B subunit

Synonyms: BIII, Brain calcium channel III, CACH5, CACNA1B, CACNL1A5, CACNN, Cav2.2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:200-1:1000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab01171(CACNA1B Antibody) at dilution of 1:100 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab01171(CACNA1B antibody) at dilution of 1:300

Gene ID: 774

Research Area: Metabolism

Uniprot ID: Q00975