Product Description
anti- CAD antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms..
Immunogen: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Synonyms:
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Image 1: Immunohistochemistry of paraffin-embedded human liver using FNab01183(CAD antibody) at dilution of 1:100
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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab01183(CAD antibody) at dilution of 1:1000
Gene ID: 790
Research Area: Metabolism
Uniprot ID: P27708