anti- Caspase 1 antibody

Product Description

anti- Caspase 1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta(IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products(PMID:21804020). It has 5 isoforms produced by alternative splicing. .

Immunogen: caspase 1

Synonyms: CASP 1, CASP1, Caspase 1, Caspase 1/p20/p10, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1BC, IL1BCE, Interleukin 1 beta convertase, p10, p20, P45

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:200-1:2000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human stomach tissue slide using FNab10015(CASP1 Antibody) at dilution of 1:100

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Image 4: NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab10015(CASP1 antibody) at dilution of 1:1000

Gene ID: 834

Research Area: Metabolism

Uniprot ID: P29466