anti- Caspase 8 antibody

Product Description

anti- Caspase 8 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibodycan recognize pro-and cleaved-caspase 8..

Immunogen: caspase 8, apoptosis-related cysteine peptidase

Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch 5, Casp 8, CASP8, Caspase 8, Caspase 8/p18, Caspase8, FADD like ICE, FLICE, ICE like apoptotic protease 5, MACH, MCH5

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded mouse kidney using FNab10024(CASP8 antibody) at dilution of 1:100

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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab10024(CASP8 antibody) at dilution of 1:1000

Gene ID: 841

Research Area: Metabolism

Uniprot ID: Q14790