Product Description
anti- Caveolin-1 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: Caveolin-1 is a protein that in humans is encoded by the CAV1 gene.The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene..
Immunogen: caveolin 1, caveolae protein, 22kDa
Synonyms:
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human lung cancer using FNab01314(CAV1 antibody) at dilution of 1:50
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Image 4: PC-3 cells were subjected to SDS PAGE followed by western blot with FNab01314(CAV1 antibody) at dilution of 1:1000
Research Area: Metabolism
Uniprot ID: Q03135