anti- CBX3 antibody

Product Description

anti- CBX3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene..

Immunogen: chromobox homolog 3 (HP1 gamma homolog, Drosophila)

Synonyms:

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human lung cancer using FNab01330(CBX3 antibody) at dilution of 1:100

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab01330(CBX3 antibody) at dilution of 1:1000

Gene ID: 11335

Research Area: Metabolism

Uniprot ID: Q13185