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Product Description
anti- CD14 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211)..
Immunogen: CD14 molecule
Synonyms: CD14, CD14 molecule
Reactivity: Human
Tested Application: ELISA, IHC
Recommended dilution: IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab10077(CD14 Antibody) at dilution of 1:200
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Gene ID: 929
Research Area: Metabolism
Uniprot ID: P08571
