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Product Description
anti- CD150 antibody(PE conjugated) is available at Gentaur for Next week Delivery.
Purification: Protein G purified
Background: CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoieticstem cell studies. .
Immunogen: signaling lymphocytic activation molecule family member 1
Synonyms: CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906
Reactivity: Mouse
Tested Application: FC
Recommended dilution: 1?10-1?50
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Research Area: Metabolism
Uniprot ID: Q9QUM4
