anti- CD206 antibody

Product Description

anti- CD206 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains(responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia..

Immunogen: mannose receptor, C type 1

Synonyms: CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:200-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

Image 1: Immunohistochemistry of paraffin-embedded human lung using FNab09912(CD206 antibody) at dilution of 1:100

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Image 4: Mouse liver were subjected to SDS PAGE followed by western blot with FNab09912(CD206 antibody) at dilution of 1:1000

Gene ID: 4360

Research Area: Metabolism

Uniprot ID: P22897