anti- CD320 antibody

Product Description

anti- CD320 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: CD320, also known as 8D6, 8D6A or TCblR, is a single-pass type I membrane protein containing 2 LDL-receptor class A domains. Expressed abundantly on follicular dendritic cells (FDCs), CD320 has been shown to enhance proliferation of germinal center (GC) B cells. It is the receptor for cellular uptake of transcobalamin-bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC). CD320 has a calculated molecular mass of 29 kDa. This antibody detects bands at 50-55 kDa and 60-70 kDa, probably caused by extensive complex glycosylation..

Immunogen: CD320 molecule

Synonyms: 8D6, 8D6 antigen, 8D6A, CD320, CD320 antigen, CD320 molecule, FDC signaling molecule 8D6, FDC SM 8D6, TCblR, Transcobalamin receptor

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:1000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis using FNab01466(CD320 antibody) at dilution of 1:50

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01466(CD320 antibody) at dilution of 1:500

Gene ID: 51293

Research Area: Metabolism

Uniprot ID: Q9NPF0