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Product Description
anti- CD33 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia(in vitro)..
Immunogen: CD33 molecule
Synonyms: SIGLEC3
Reactivity: Human
Tested Application: ELISA, WB, IHC, IF
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human spleen using FNab01467(CD33 antibody) at dilution of 1:100
Image 2: .
Image 3:
Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab01467(CD33 antibody) at dilution of 1:600
Gene ID: 945
Research Area: Metabolism
Uniprot ID: P20138
