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Product Description
anti- CD79A antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells..
Immunogen: CD79a molecule, immunoglobulin-associated alpha
Synonyms: CD79A, Ig alpha, IGA, MB 1, MB 1 membrane glycoprotein, MB1, Surface IgM associated protein
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01499(CD79A Antibody) at dilution of 1:200
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Image 4: Raji cells were subjected to SDS PAGE followed by western blot with FNab01499(CD79A antibody) at dilution of 1:1000
Gene ID: 973
Research Area: Metabolism
Uniprot ID: P11912
