Euro
British Pound
US Dollar
Product Description
anti- CDC14B antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome(APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases..
Immunogen: CDC14 cell division cycle 14 homolog B(S. cerevisiae)
Synonyms:
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution:
Image 1:
Image 2: .
Image 3:
Image 4: SMMC-7721 cells were subjected to SDS PAGE followed by western blot with FNab01516( CDC14B Antibody) at dilution of 1:300
Gene ID: 8555
Research Area: Metabolism
Uniprot ID: O60729
